Photobiomodulation: Harnessing Light for Health and Wellness
Article

Photobiomodulation: Harnessing Light for Health and Wellness

Published on Thursday, September 18, 2025
by
Piedad Cardona

Wellness

Photobiomodulation (PBM): Red Light Therapy Benefits for Skin, Pain, and Brain Health

Introduction

Photobiomodulation (PBM), also known as red or near-infrared light therapy, is a fascinating way our cells can use light to function better. At its core, PBM interacts with the mitochondria—the energy centers of our cells—helping them produce more energy and support natural repair processes.

Over the past few years, research has shown that PBM may benefit many aspects of health, from supporting skin and muscles to aiding recovery and even influencing brain function. Today, with a variety of devices available for home use, it’s possible to explore PBM safely and thoughtfully as part of a daily wellness routine.

In this article, we’ll look at how PBM works, the types of devices available, and the ways it can support skin, muscle, pain, and brain health—all based on current science.

What is PBM and How Does it Work?

Photobiomodulation, or red/near-infrared light therapy, is a technique that uses specific wavelengths of light to influence cellular function. PBM primarily targets the mitochondria, which are responsible for producing energy in cells.

When light is absorbed by cytochrome c oxidase, an enzyme in the mitochondria, cells produce more ATP—the molecule that powers most cellular processes. This increase in energy can help cells repair themselves, reduce oxidative stress, and improve overall function.

The effects of PBM have been studied across many areas, including skin health, muscle recovery, pain management, and even brain function.

Accessibility of PBM Devices for Home Use

What was once available only in clinics is now increasingly accessible through safe, at-home devices. Some common options include:

  • LED face masks – primarily for skin rejuvenation and mild skin conditions.

  • Handheld wands – for targeted areas like joints, small muscle groups, or specific skin spots.

  • Panels – larger devices for broader coverage, often used for muscles, recovery, or general wellness.

  • Wearable helmets or caps – designed to deliver light to the brain to support cognitive function.

  • Intranasal devices – small applicators that emit light through the nasal cavity, supporting circulation and neural activity.

These devices are generally easy to use, but protocols vary depending on the purpose and device type.

Practical Applications of PBM

Skin Health

PBM can stimulate collagen production and improve circulation, which may help with skin tone, elasticity, and repair. Sessions are typically 10–20 minutes, 3–5 times per week, depending on the device and the area being treated.

Pain Relief and Muscle Recovery

By increasing mitochondrial energy and supporting circulation, PBM can help reduce inflammation and support recovery in muscles and joints. Panels and wands are commonly used to target areas of soreness or stiffness. Regular sessions over several weeks may provide noticeable benefits.

Brain Health

Near-infrared light can penetrate the skull and influence neuronal function. PBM in the brain may:

  • Enhance mitochondrial activity in neurons

  • Improve cerebral blood flow.

  • Reduce oxidative stress and neuroinflammation.

  • Support memory, focus, and mood

Supporting research:

  • Studies on mild traumatic brain injury have found PBM improves cognitive function and reduces symptoms.

  • Pilot studies in cognitive decline and dementia suggest improvements in attention, memory, and sleep.

  • Early Alzheimer’s research indicates potential benefits for cognition and behavioral symptoms, although larger studies are needed.

Typical PBM sessions for brain health last 10–20 minutes, 3–5 times per week. Devices include helmets, caps, and intranasal light applicators.

Conclusion

Photobiomodulation is a science-backed method of supporting cellular function. By energizing mitochondria and enhancing natural repair processes, PBM has potential benefits for skin, muscles, pain, and brain health.

With a range of devices now available for home use, it is possible to explore PBM thoughtfully and safely as part of a daily wellness approach. While research continues, current studies provide a growing understanding of how light can influence health at the cellular level.

 

  1. Avci, P., Gupta, A., Sadasivam, M., Vecchio, D., Pam, Z., Pam, N., & Hamblin, M. R. (2013). Low-level laser (light) therapy (LLLT) in skin: Stimulating, healing, restoring. Seminars in Cutaneous Medicine and Surgery, 32(1), 41–52. https://doi.org/10.12788/j.sder.2013.032 

  2. Barrett, D. W., & Gonzalez-Lima, F. (2013). Transcranial infrared laser stimulation produces beneficial cognitive and emotional effects in humans. Neuroscience, 230, 13–23. https://doi.org/10.1016/j.neuroscience.2012.11.015 

  3. Chung, H., Dai, T., Sharma, S. K., Huang, Y. Y., Carroll, J. D., & Hamblin, M. R. (2012). The nuts and bolts of low-level laser (light) therapy. Annals of Biomedical Engineering, 40(2), 516–533. https://doi.org/10.1007/s10439-011-0454-7 

  4. Gonzalez-Lima, F., & Barrett, D. W. (2014). Low-level light therapy (photobiomodulation) for cognitive enhancement: Mechanisms and applications. Frontiers in Neuroscience, 8, 330. https://www.frontiersin.org/articles/10.3389/fnins.2014.00330/full 

  5. Hamblin, M. R. (2017). Mechanisms and applications of the anti-inflammatory effects of photobiomodulation. AIMS Biophysics, 4(3), 337–361. https://doi.org/10.3934/biophy.2017.3.337 

  6. Leal Junior, E. C. P., Vanin, A. A., Miranda, E. F., de Carvalho, P. D. T., Dal Corso, S., & Bjordal, J. M. (2015). Effects of phototherapy (low-level laser therapy) on exercise performance and skeletal muscle recovery: A systematic review. Lasers in Medical Science, 30(2), 925–939. https://doi.org/10.1007/s10103-014-1668-2 

  7. Naeser, M. A., Saltmarche, A., Krengel, M. H., Hamblin, M. R., & Knight, J. A. (2011). Improved cognitive function after transcranial, light-emitting diode treatments in chronic, traumatic brain injury: Two case reports. Photomedicine and Laser Surgery, 29(5), 351–358. https://doi.org/10.1089/pho.2010.2819

  8. Salehpour, F., Mahmoudi, J., & Hamblin, M. R. (2018). Brain photobiomodulation therapy: A narrative review. Molecular Neurobiology, 55(8), 6601–6636. https://doi.org/10.1007/s12035-018-1124-6

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