Taking a Closer Look: Vitamin D Deficiency and Irritable Bowel Syndrome
Article

Taking a Closer Look: Vitamin D Deficiency and Irritable Bowel Syndrome

Published on Friday, May 13, 2022
by
Emily Hamm

Health & Wellness

Vitamin D and Gut Health: Why It Matters More Than You Think


Did you know?? There is SO MUCH ongoing research surrounding vitamin D and its vital role in human health.

First off, let’s talk about what vitamin D actually is. As a fat-soluble vitamin, it is found naturally in a small number of foods and added to others. Our bodies also produce vitamin D through exposure to UV light, which triggers its synthesis in the skin. On top of that, vitamin D can also be obtained through supplementation when needed.

Vitamin D plays a role in a wide range of functions in the body, including supporting bone health, regulating inflammation, strengthening immune function, assisting with cell growth and turnover, contributing to neuromuscular function, and even influencing glucose metabolism.

ALSO…

Our gut health is fundamental to immune function and the control of inflammation, which is where things start to connect.

The Gut–Vitamin D Connection

If you suffer from gastric motility disorders—such as IBS, chronic functional constipation, or intestinal pseudo-obstruction—you may also struggle with digesting and absorbing certain micronutrients, including vitamin D.

This is where the research gets especially interesting.

A study by Linsalata et al. found a strong association between vitamin D status and altered intestinal barrier function in patients with IBS-D following a long-term Low-FODMAP diet.

The authors found that individuals with lower vitamin D levels experienced significantly worse symptoms and showed changes in small intestinal permeability, sometimes referred to as a “leaky gut” effect.

After following a Low FODMAP diet for 12 weeks, participants not only experienced symptom improvement but also saw increased vitamin D levels, suggesting that dietary intervention may help support both gut integrity and nutrient status.

This highlights something important—when we improve gut health, we may also improve the body's ability to absorb and utilize key nutrients.

How Do You Know If You Have Enough Vitamin D?

The best way to determine your vitamin D status is through a simple blood test ordered by your primary care provider. This is often included in routine lab work and is typically covered by insurance.

If your levels are low—generally considered below 30 nmol/L—your provider may recommend supplementation. Depending on your needs, this could be a prescription-strength dose or a standard over-the-counter option.

Ways to Support Healthy Vitamin D Levels

There are a few simple ways to support your vitamin D levels in everyday life. Spending time outdoors is one of the most natural approaches. Around 30 minutes of sunlight exposure each day can help your body produce vitamin D, although it’s important to balance this with safe sun practices to avoid skin damage.

Diet also plays a role. Foods such as fatty fish (like salmon, cod, sardines, and tuna), eggs, liver, fortified dairy or dairy alternatives, fortified cereals, tofu, shiitake mushrooms, and even fortified orange juice can contribute to your intake.

That said, if you are managing IBS, it’s important to individualize these choices. Some of these foods may not sit well for everyone, and that’s okay. Working with a Registered Dietitian can help you identify what works best for your body while still meeting your nutritional needs.

The Bottom Line

Vitamin D plays a critical role in overall health, but its connection to gut health—especially in conditions like IBS—is an emerging area that deserves attention.

Lower vitamin D levels may be associated with more severe gastrointestinal symptoms and impaired gut barrier function, while improving gut health through dietary strategies may help restore both symptom control and nutrient status.

A simple blood test, combined with thoughtful nutrition and lifestyle choices, can go a long way in supporting both your gut and your overall well-being.


  1. Linsalata, M., Riezzo, G., Orlando, A., D’Attoma, B., Prospero, L., Tutino, V., Notarnicola, M., & Russo, F. (2021). The relationship between low serum vitamin D levels and altered intestinal barrier function in patients with IBS diarrhea undergoing a long-term low-FODMAP diet: Novel observations from a clinical trial. Nutrients, 13(3), 1011. https://doi.org/10.3390/nu13031011 
  2. U.S. Department of Health and Human Services. (2025, June 27). Office of dietary supplements - vitamin D. NIH Office of Dietary Supplements. https://ods.od.nih.gov/factsheets/VitaminD-HealthProfessional/ 

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